Purcell reprises his role as Michael's fiercely loyal older brother. After receiving a cryptic photo showing Michael alive, Lincoln abandons his quiet life to lead a new, dangerous rescue mission into war-torn Yemen.

Miller returns as the genius structural engineer presumed dead for years. In Season 5, Michael is revealed to be alive, imprisoned in a Yemeni prison called Ogygia, and using a new alias, "Kaniel Outis" – a known terrorist.

The ever-loyal best friend to Michael, Sucre joins the rescue team without hesitation, providing both muscle and heartfelt support.

The young son of Michael and Sara, whose existence becomes a powerful motivator for his father to finally escape his past for good.

The former Secret Service agent returns, now a high-ranking U.S. government official. He provides crucial (but ambiguous) intelligence about Michael’s situation.

A sadistic and eccentric killer, Van Gogh serves as A&W’s partner, bringing a volatile and unpredictable menace to Poseidon’s operations.

A fellow inmate in Ogygia, Sid forms a close bond with Michael and helps him from inside the prison.